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Perl is the programming language most often used in the bioinformatics realm, and it is the language most often used by GMOD developers. It is well-suited to text and data processing and is also characterized by an extensive open source library, so it's highly functional. Many of GMOD components use BioPerl, a bioinformatics toolkit written in Perl.

Some pieces of GMOD, like GBrowse, can be extended or customized using Perl but beginners' skills in Perl would be sufficient for this work.

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